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The United States Medical Licensing Examination (USMLE) can be considered a milestone in the path of medical students who dream of having a career in the United States. Moreover, it determines the ability of the student or graduate to use major concepts, knowledge and principles that require safe and effective patient care. However, when you are already busy with the rigorous course of MBBS, you might feel confused preparing to take the USMLE. Consequently, the trick is to be smart in integration. That means aligning your MBBS subjects with the USMLE syllabus and planning a structured, year-wise preparation strategy.


In this guide, we will take you through a step-by-step, year-by-year plan of preparing in your MBBS years to ensure that you will not only fix the basics of the USMLE Step 1 but will also complete the USMLE Step 2 CK without making any extra effort.

What Is the USMLE Syllabus?

Before planning your preparation, you need to understand what you are studying for. The USMLE is made up of three steps.

  • Step 1, you will be tested in the basic sciences, which include Anatomy, Physiology, Biochemistry, Pathology, Pharmacology, Microbiology, and Behavioural Sciences.
  • Step 2 CK (Clinical Knowledge) assesses your understanding of clinical topics such as Medicine, Surgery, Paediatrics, Psychiatry, and Obstetrics and Gynaecology.
  • Step 3 follows graduation and is aimed at utilising the knowledge related to medicine during unattended clinical practice.

In MBBS, you will have to concentrate mainly on USMLE Step 1 and Step 2 CK since Step 3 is normally taken during or after residency.

1st Year MBBS - Build a Strong Foundation

  • You will be introduced to the fundamental subjects Anatomy, Physiology, and Biochemistry this year: these are the foundations of USMLE Step 1.
  • Begin gradually by getting to know First Aid for the USMLE Step 1. Moreover, take advantage of extra resources such as Boards and Beyond to understand concepts and Anki flash cards when revising concepts. Biochemical Sketchy is really useful in memorisation.
  • At this point, studying 4-5 hours a week is sufficient. Moreover, learn, rather than memorise; this is the foundation of all that will follow.

2nd Year MBBS - Core Step 1 Preparation

  • The high-yield topics in the USMLE Step 1 syllabus include such topics as Pathology, Microbiology, and Pharmacology.
  • Use Pathoma on pathology, sketchy on micro and pharm and start solving UWorld step 1 MCQs with QBank. Moreover, integrate your MBBS with a USMLE study plan by matching the two plans. It is the best moment to do the annotation of First Aid and practice solving questions. Allocate about 6-8 hours a week to keep it steady and become confident.

3rd Year MBBS - Start Bridging Step 1 and Step 2 CK

  • The 3rd year is easier with subjects such as Community Medicine, ENT, and Ophthalmology; together, you can get time to revise Step 1 and gradually get into Step 2 CK.
  • You should use this year to begin USMLE preparation for clinical subjects (with OnlineMedEd or AMBOSS) and to complete a revision of Step 1. Further, include Step 2 style MCQs, particularly case-based questions, to develop clinical thought. It is best to have a regular 4-6 hours per week.

4th Year MBBS - Strong Focus on Step 2 CK

  • This year tackles big clinical topics: Internal Medicine, Surgery, Paediatrics, OBGYN, and Psychiatry, all necessary to pass Step 2 CK.
  • Solve concept-based UWorld Step 2 CK QBank questions on what you learn in MBBS. A couple of videos of OnlineMedEd with hospital postings to reinforce clinical reasoning. Besides, begin to use NBME self-assessments to monitor progress.
  • Invest 8-10 hours per week in solving questions and relearning notes taken in previous years.

Final Year MBBS - Reinforce & Apply Clinical Knowledge

  • By the final year, you are expected to have gained wide clinical exposure, which plays a crucial role in preparing for the USMLE during MBBS. This is the time to familiarise yourself with applying medical knowledge in real-world scenarios — an essential technique tested in USMLE Step 2 CK.
  • It is time to solidify all your clinical knowledge by reading high-yield notes, UWorld blocks, and simulation examinations. Make a systematic revision program that goes through the big specialities and incorporates your experience with the MBBS internship.
  • Be sure to be familiar with patient management situations, interpretation of diagnosis, and time-limited decision making. An intelligent mix can yield excellent outcomes even to the extent of 1-2 hours per day.

Internship - Final Revision & USMLE Attempts

  • The internship would be your best opportunity to take Step 1 (if you have not already taken it) and Step 2 CK. Gaining exposure to practice and almost finishing MBBS, focus on full-length mock tests, repeating questions of QBank, and brushing up on the weak spots.
  • This is also the time to start your ECFMG application process and collect your transcript copies or LORs in case you intend to apply to the U.S. residencies.

Final Thoughts!

Having learned how to correlate each year of MBBS with the USMLE syllabus and preparation program, it becomes evident that the YEAR-wise method greatly diminishes the level of the exams' stressful component, and provides quite a good chance of passing successfully. Rather than trying to cram it all during the last year, it is better to start early and increase incrementally so that by the time you are finally taking the USMLE exams, retention is high, clinical knowledge is good, and you are more confident.

Additionally, whether you are in a first year mastering all your basic sciences or sharpening clinical decision-making closer to graduation, every stage of your MBBS life can play a significant role in your USMLE success, as long as you take it the right way. And if you have certain questions or require individual assistance, you are welcome to discuss your concerns with the academic team at Lincoln American University, and we will be happy to assist you at any stage.

FAQs

Q.1. Is USMLE easy for Indian students?

Ans - It is not that USMLE is a very simple course; however, with the proper planning and preparation early in the course, Indian students can successfully pass it.

Q.2. Is USMLE Step 1 harder than NEET?

Ans - Yes, USMLE Step 1 is usually more conceptual and clinically centred as compared to NEET, which makes it quite difficult for most students.

Q.3. Which is the toughest medical exam in the world?

USMLE, PLAB, and AMC are the most difficult medical examinations worldwide and it may be said that USMLE is the most difficult because it is deep and multi-step.

Q.4. What if I fail in USMLE Step 1?

In case you fail USMLE Step 1 once, you will still be able to retake it, but there are not many attempts, and it might impact the overall competitiveness of your application to a residency.